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4% in the Actonel 5 mg daily group and 1. 5%) in each treatment arm (placebo and Actonel 5 mg once daily). There were no significant differences in serum calcium, phosphate, or PTH levels between placebo and Actonel 5 mg once daily at 3 years. 2% in the Actonel 5 mg daily group and 13. In postmenopausal women with osteoporosis, Actonel reduces the incidence of vertebral fractures and a composite endpoint of nonvertebral osteoporosis-related fractures [see Clinical Studies (14.
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